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1.
Zhongguo Zhong Yao Za Zhi ; 40(18): 3660-3, 2015 Sep.
Artigo em Chinês | MEDLINE | ID: mdl-26983217

RESUMO

Currently, the herbal prescription therapy for corresponding constitutional diseases is a common constitution regulating method. This method has an obvious effect in treating and regulating constitution-related diseases. However, for people who do not have disease, they prefer to regulate constitution with dietary therapy. In this paper, the researchers came up with a design method of constitution regulating and healthcare foods based on medicinal property combination mode of clinical empirical formulas. With "Yupinfeng San", a common formula for Qi-insufficiency constitution and specific endowment constitution, as the example for constitution regulating and healthcare foods, the researchers proved the effectiveness and rationality of healthcare food schemes in terms of the efficacy of single herb and the modern pharmacological study.


Assuntos
Dietoterapia , Plantas Medicinais/metabolismo , Dieta , Humanos , Plantas Medicinais/química , Prescrições
2.
Zhongguo Zhong Yao Za Zhi ; 40(18): 3664-6, 2015 Sep.
Artigo em Chinês | MEDLINE | ID: mdl-26983218

RESUMO

Based on databases for herbal properties of formulas and foods recorded in "Treatise on Febrile Diseases", a case study was conducted for the food matching method according to herbal properties of formulas in "Treatise on Febrile Diseases". The result show that the method was technically feasible once the herbal properties of foods were determined. Moreover, according to herbal properties of target formulas, the compositions of foods were effectively defined. In this study, researchers determined the similarity between the food matching scheme and the target formulas in function and efficacy, provided a quantitative method for food formulation and promote the development of application technology of the herbal property theory and the compatibility theory.


Assuntos
Livros/história , Medicamentos de Ervas Chinesas/química , Plantas Medicinais/química , China , Dietoterapia/história , Medicamentos de Ervas Chinesas/história , Medicamentos de Ervas Chinesas/metabolismo , Alimentos/história , História Antiga , Medicina na Literatura , Plantas Medicinais/metabolismo
3.
Zhongguo Zhong Yao Za Zhi ; 39(13): 2378-81, 2014 Jul.
Artigo em Chinês | MEDLINE | ID: mdl-25276946

RESUMO

The combination of medicinal properties refers to expression forms of elements with active properties combined according to a specific sequence. The mode of medicinal property combination refers to the compatible relationship multiple medicinal property combinations. In this paper, based on the mode, safflower, Taohong Siwu decoction, Xuefu Zhuyu decoction and Buyang Huanwu decoction were taken for example to study the characteristics of the compatibility among single herb, herbal pairs and prescriptions. The authors discovered the similarities and differences among them, interpreted the self-similarity in medicinal property combinations of traditional Chinese medicines, and analyzed the compatible relationship among multiple medicinal property combinations, so as to bring forth new ideas in discovering the correlation between the compatibility study mode of traditional Chinese medicines based medicinal property combinations and the efficient compatibility of medicinal property combination.


Assuntos
Medicamentos de Ervas Chinesas/química , Medicamentos de Ervas Chinesas/farmacologia , Medicina Tradicional Chinesa , Combinação de Medicamentos , Prescrições de Medicamentos , Tratamento Farmacológico , Humanos
4.
Zhongguo Zhong Yao Za Zhi ; 39(13): 2389-91, 2014 Jul.
Artigo em Chinês | MEDLINE | ID: mdl-25276949

RESUMO

Multi-component traditional Chinese medicines are an innovative research mode for traditional Chinese medicines. Currently, there are many design methods for developing multi-component traditional Chinese medicines, but their common feature is the lack of effective connection of the traditional Chinese medicine theory. In this paper, the authors discussed the multi-component traditional Chinese medicine design methods based on medicinal property combination modes, provided the combination methods with the characteristics of traditional Chinese medicine for the prescription combinations, and proved its feasibly with hypertension cases.


Assuntos
Anti-Hipertensivos/administração & dosagem , Medicamentos de Ervas Chinesas/administração & dosagem , Hipertensão/tratamento farmacológico , Animais , Anti-Hipertensivos/química , Pressão Sanguínea/efeitos dos fármacos , Combinação de Medicamentos , Tratamento Farmacológico , Medicamentos de Ervas Chinesas/química , Humanos , Hipertensão/fisiopatologia , Medicina Tradicional Chinesa , Ratos
5.
Zhongguo Zhong Yao Za Zhi ; 39(13): 2392-5, 2014 Jul.
Artigo em Chinês | MEDLINE | ID: mdl-25276950

RESUMO

To propose a formula method of medicated diet based on medicinal property combination patterns in this paper under the context of lack of innovation in medicated diets. By analyzing the property combination patterns of traditional Chinese medicine and commonly used foods recorded in the pharmacopoeia, medicated diet formulae were optimized by using the greedy algorithm, with the property combination patterns of classical formulae based on the syndrome differentiation and treatment. In this paper, the Baihu Rensheng decoction, which is a classical formula for treating lung and stomach heat-derived diabetes, was taken for example in the formula design. As a result, totally 18 medicated diet formulae were developed and proved to be rational in the analysis on traditional Chinese medicines and nutriology. This method expands the way of thinking for personalized diet therapies and provides theoretical basis the industrial development and clinical application of medicated diets.


Assuntos
Diabetes Mellitus/dietoterapia , Diabetes Mellitus/tratamento farmacológico , Dietoterapia , Medicamentos de Ervas Chinesas/química , Fitoterapia , Animais , Diabetes Mellitus/metabolismo , Dieta , Medicamentos de Ervas Chinesas/uso terapêutico , Humanos
6.
Artigo em Inglês | MEDLINE | ID: mdl-25214873

RESUMO

Plants from Asteraceae family are widely used as herbal medicines and food ingredients, especially in Asian area. Therefore, authentication and quality control of these different Asteraceae plants are important for ensuring consumers' safety and efficacy. In recent decades, electronic nose (E-nose) has been studied as an alternative approach. In this paper, we aim to develop a novel discriminative model by improving radial basis function artificial neural network (RBF-ANN) classification model. Feature selection algorithms, including principal component analysis (PCA) and BestFirst + CfsSubsetEval (BC), were applied in the improvement of RBF-ANN models. Results illustrate that in the improved RBF-ANN models with lower dimension data classification accuracies (100%) remained the same as in the original model with higher-dimension data. It is the first time to introduce feature selection methods to get valuable information on how to attribute more relevant MOS sensors; namely, in this case, S1, S3, S4, S6, and S7 show better capability to distinguish these Asteraceae plants. This paper also gives insights to further research in this area, for instance, sensor array optimization and performance improvement of classification model.

7.
Artigo em Inglês | MEDLINE | ID: mdl-25114708

RESUMO

Identification of Chinese herbal medicines (CHMs) by human experience is often inaccurate because individual ability and external factors may influence the outcome. However, it might be promising to employ an electronic nose (E-nose) to identify them. This paper presents a rapid and reliable method for identification of ten different species of CHMs from Zingiberaceae family based on their response signals from E-nose. Ten Zingiberaceae CHMs were measured and their maximum response values were analyzed by principal component analysis (PCA). Result shows that E Zhu (Curcuma phaeocaulis Val.) and Yi Zhi (Alpinia oxyphylla Miq.) could not be distinguished completely by PCA. Two solutions were proposed: (i) using BestFirst+CfsSubsetEval (BC) method to extract more discriminative features to select sensors with higher contribution rate and remove the redundant signals; (ii) employing a novel cascade classifier with two stages to enhance the distinguishing-positive rate (DPR). Based on these strategies, six features were extracted and used in different stages of the cascade classifier with higher DPRs.

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